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Factor Supply High Quality Formamide CAS 75-12-7 with Stock

Organic Intermediate

Factor Supply High Quality Formamide CAS 75-12-7 with Stock

English Name:Formamide

CAS: 75-12-7

Category: Organic intermediates

Physical property: Formamide is colorless, odorless oily liquid with a slight ammonia odor when containing impurities. It is hygroscopic. Relative molecular mass 45.04. The relative density is 1.1334. Melting point 2.55℃. Boiling point 210.5℃. Refractive index 1.4475Chemicalbook. Flash point 154℃. Viscosity 3.76mPa·s(20℃). Insoluble in ethers and chlorine-containing solvents, slightly soluble in benzene, can be miscible with water, methanol, ethanol, acetic acid, acetone, dioxane, ethylene glycol, phenol and low esters.

    Nature

    Product name Formamide CAS 75-12-7
    Appearance Colorless liquid Purity 99%
    Molecular formula CH3NO Molecular weight 45.04
    Melting point 2-3 °C(lit.) Boiling point 210 °C(lit.)
    Density 1.134 g/mL at 25 °C(lit.) Refractive index n20/D 1.447(lit.)

    application

    Formamide has active reactivity and special dissolution ability, can be used as organic synthesis raw material, paper treatment agent, fiber industry softener, animal glue softener, and also used as an analytical reagent to determine the amino acid content in rice. In organic synthesis, the use of medicine is mostly, and there are many uses in pesticides, dyes, pigments, spices, auxiliaries. It is also an excellent organic solvent, mainly used in spinning and ion exchange resins of acrylonitrile copolymers, as well as anti-static coating or conductive coating of plastic products. In addition, it is also used to separate chlorosilane, purify oil and so on. Formamide can undergo a variety of reactions. In addition to the reaction involving three hydrogens, it can also undergo dehydration, deCO, introduction of amino group, introduction of acyl group and cyclization. Take loop union as an example. Diethyl malonate is cyclically combined with formamide to obtain 4, 6-dihydroxypyrimidine, an intermediate of vitamin B4. Anthranilic acid was combined with amide to obtain the antiarrhythmic intermediate quinazolone-4. The xanthine oxidase inhibitor allopurinol was obtained by the cyclic synthesis of 3-amino-4-ethoxycarbonyl pyrazole with formamide. Ethylenediamine tetraacetic acid was synthesized with formamide to obtain the anticancer drug ethylimide. Methyl ethyl methoxymalonate is cyclically combined with formamide to obtain the intermediate of sulfonamides, 5-methoxy-4, 6-dihydroxypyrimidine disodium.

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